I'm always looking for cool keyboard short cuts to help me be more productive in my applications. For example, Visual Studio has a gazillion shortcut keys that enables you to do just about anything without the mouse. I find that while I'm coding, the less time I use switching back and forth between the keyboard and the mouse the more I get done. But what if you aren't in your favorite development environment. Here is a great list of windows shortcut keys from CodingHorror.
If you wish to expand on this list, you might want to try Winkeys. Winkeys allows you to use the Windows key to create keyboard shortcuts for your favorite applications. Here is a list of the ones that I have added. For example, I use Windows + Shift + V to open Visual Studio 2005.